Niche capabilities
Simpler manufacturing via greener reactions
Illustrative examples of how we apply first-principles thinking, process innovation and commercial focus to complex chemistry challenges.
01
On-demand hydrogenation at room temperature
Advantages
No capital investmentBatches planned as requiredNo pressureNo specialised manpowerSafer and greener than conventional methods
02
Dehydrogenation / oxidation with air
Advantages
Green chemistryNon-bromine routeFewer impuritiesHigher yieldEasy scale-upVolume efficient
03
Catalytic trans-esterification
Advantages
Room-temperature trans-esterificationEnergy efficientWorks at scaleApplicable to biodiesel
04
N-alkylation in water
Advantages
Green chemistryHigher yieldEase of operationUsed in pharma intermediate synthesis
Case study · Intermediate synthesis
Redesigning an 11-step route to a key intermediate
First-principles route redesign to improve manufacturability, reduce cost and eliminate hazardous steps.
~120°Cdown from 230–250°C
11→5process steps
ParameterChallengeNuSynth outcome
Steps
11-step route
4–5 steps
Temperature
230–250°C high-temperature step
~120°C
Reagents
Hazardous reagents (phosgene, bromine)
Phosgene- and bromine-free pathway
Raw materials
Import-dependent
Locally available raw materials
Cost
Higher-cost legacy route
Significantly lower process cost
On-demand chemistry
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Partner with us to co-develop custom molecules and synthetic routes for your most challenging targets.